Herbal therapy is becoming increasingly popular among patients and physicians. Many herbal preparations are marketed to the public for various skin conditions. Herbal therapies have been used sucessfully in treating dermatologic disorders for thousand’s of years in Europe and Asia. In Germany, a Regulatory Commission oversees herbal preparations and recommended uses. In Asia, herbal treatments that have been used for centuries are now being studied scientifically. In the US, the FDA does not regulate herbal products, as they are considered dietary supplements, therefore, there is no standardization of active ingredients, purity or concentration. There are also no regulations governing which herbs can be marketed for various ailments which has made learning about and using these treatments challenging. We reviewed the scientific evidence of clinical efficacy of the herbal medications and the more common herbs useful in the treatment of dermatologic disorders. Knowledge about the safety of the herbs have been shown to better enable the physician to know which herbal therapies they may want to use in practice. As seen in the dermatologic setting, we also studied common drug interactions and side effects of herbal medicines.